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Zhong-Gao WANG MD, FACS, Feng JI MD, PhD, Yun-Gang LAI MD, PhD, Xiang GAO MD, PhD, Cheng-Chao ZHANG MD, PhD, Ji-Min WU MD, PhD, Xiu CHEN MD, PhD, Ibrahim M. IBRAHIM MD, FACS,
《医学前沿(英文)》 2010年 第4卷 第2期 页码 254-258 doi: 10.1007/s11684-010-0029-2
关键词: gastroesophageal reflux disease pH monitoring laparoscopic fundoplication respiratory symptom
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《医学前沿(英文)》 2018年 第12卷 第2期 页码 189-195 doi: 10.1007/s11684-017-0533-8
Obstructive sleep apnea syndrome (OSAS) increases the risk of post-surgery complications. This study uses Berlin Questionnaire (BQ) to identify Chinese adult surgical patients who are at a high risk of OSAS and to determine if the BQ could be used to detect potential high risk of adverse respiratory events in the post anesthesia care unit (PACU). Results indicated that only 11.4% of the patients were considered at a high risk of OSAS. Age and body mass index are the key factors for the risk of OSAS prevalence in China and also gender specific. Furthermore, the incidence of adverse respiratory events in the PACU was higher in patients with high risk of OSAS than others (6.8% vs. 0.9%, <0.001). They also stayed longer than others in the PACU (95±28 min vs. 62±19 min, <0.001). Age, high risk for OSAS, and smoking were independent risk factors for the occurrence of adverse respiratory events in the PACU. The BQ may be adopted as a screening tool for anesthesiologists in China to identify patients who are at high risk of OSAS and determine the potential risk of developing postoperative respiratory complications in the PACU.
关键词: obstructive sleep apnea Berlin Questionnaire Chinese surgical patients adverse respiratory event
《医学前沿(英文)》 doi: 10.1007/s11684-023-1011-0
关键词: Paxlovid hemodialysis SARS-CoV-2 viral load chest CT scan
Middle East respiratory syndrome coronavirus: current situation and travel-associated concerns
null
《医学前沿(英文)》 2016年 第10卷 第2期 页码 111-119 doi: 10.1007/s11684-016-0446-y
The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 brought back memories of the occurrence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002. More than 1500 MERS-CoV cases were recorded in 42 months with a case fatality rate (CFR) of 40%. Meanwhile, 8000 cases of SARS-CoV were confirmed in six months with a CFR of 10%. The clinical presentation of MERS-CoV ranges from mild and non-specific presentation to progressive and severe pneumonia. No predictive signs or symptoms exist to differentiate MERS-CoV from community-acquired pneumonia in hospitalized patients. An apparent heterogeneity was observed in transmission. Most MERS-CoV cases were secondary to large outbreaks in healthcare settings. These cases were secondary to community-acquired cases, which may also cause family outbreaks. Travel-associated MERS infection remains low. However, the virus exhibited a clear tendency to cause large outbreaks outside the Arabian Peninsula as exemplified by the outbreak in the Republic of Korea. In this review, we summarize the current knowledge about MERS-CoV and highlight travel-related issues.
Sarah H. Alfaraj, Jaffar A. Al-Tawfiq, Talal A. Altuwaijri, Ziad A. Memish
《医学前沿(英文)》 2019年 第13卷 第1期 页码 126-130 doi: 10.1007/s11684-017-0603-y
关键词: Middle East respiratory syndrome coronavirus MERS-CoV pregnancy pediatrics
Early and marked up-regulation of TNF-α in acute respiratory distress syndrome after cardiopulmonary
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《医学前沿(英文)》 2012年 第6卷 第3期 页码 296-301 doi: 10.1007/s11684-012-0219-1
Despite the technique of cardiopulmonary bypass (CPB) improved the development of modern cardiac surgery, many factors during CPB have been reported to induce acute respiratory distress syndrome (ARDS). The present study was to investigate which pro-inflammatory factors involved in the early phase of ARDS. Ten patients underwent valve replacement surgery with or without ARDS were enrolled for analysis of pulmonary function and inflammatory factors release including white blood cell (WBC), neutrophils, CD11b, CD18, interleukin (IL)-8 and tumor necrosis factor-α (TNF-α). The results demonstrated that the ratio of arterial oxygen tension/fraction of inspire oxygen (PaO2/FiO2) was greatly reduced in ARDS patients, but only the release of TNF-α was significantly increased, which was reversely correlated to the values of PaO2/FiO2. Also, the count of neutrophils adhesive to pulmonary endothelial cells was significantly increased in ARDS patients. Therefore, we concluded that TNF-α was quickly up-regulated and involved in the pathogenesis of CPB-induced ARDS via guiding primed neutrophils to pulmonary interstitium.
关键词: tumor necrosis factor-α cardiopulmonary bypass inflammation acute respiratory distress syndrome
Middle East respiratory syndrome coronavirus: a comprehensive review
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《医学前沿(英文)》 2016年 第10卷 第2期 页码 120-136 doi: 10.1007/s11684-016-0430-6
The Middle East respiratory syndrome coronavirus was first identified in 2012 and has since then remained uncontrolled. Cases have been mostly reported in the Middle East, however travel-associated cases and outbreaks have also occurred. Nosocomial and zoonotic transmission of the virus appear to be the most important routes. The infection is severe and highly fatal thus necessitating rapid and efficacious interventions. Here, we performed a comprehensive review of published literature and summarized the epidemiology of the virus. In addition, we summarized the virological aspects of the infection and reviewed the animal models used as well as vaccination and antiviral tested against it.
关键词: MERS coronavirus review
Mengmeng ZHAO,Juanjuan QIAN,Jiexiong XIE,Tiantian CUI,Songling FENG,Guoqiang WANG,Ruining WANG,Guihong ZHANG
《农业科学与工程前沿(英文)》 2016年 第3卷 第2期 页码 153-160 doi: 10.15302/J-FASE-2016097
Mouth the mirror of lungs: where does the connection lie?
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《医学前沿(英文)》 2016年 第10卷 第4期 页码 405-409 doi: 10.1007/s11684-016-0476-5
Periodontitis is the chronic destructive disease of the periodontium (Gums) caused by host bacterial interactions. The effect of such host bacterial interactions in oral cavity also evokes a systemic response. Numerous studies have found common mechanisms of destruction for periodontal diseases and other chronic diseases like diabetes mellitus, atherosclerosis, respiratory diseases, and adverse pregnancy outcomes. Oral colonization by respiratory pathogens appears to be a risk factor for development of respiratory diseases and oral interventions aimed at reducing oral bacterial count have resulted in reduced incidence of these reparatory illness. This reflects the importance of oral hygiene among patients with respiratory illness. This review highlights the association between periodontal diseases and respiratory diseases.
关键词: periodontitis respiratory diseases acute pneumonia COPD
Serologic study on the outbreak of acute upper respiratory tract infections caused by adenovirus 3
JIANG Lufang, JU Liwen, LIN Yuzun, ZHOU Liandi, YU Shunzhang, JIANG Qingwu, JIANG Renjie
《医学前沿(英文)》 2007年 第1卷 第2期 页码 215-218 doi: 10.1007/s11684-007-0041-3
Jie HOU,Rui LI,Hongfang MA,Songlin QIAO,Gaiping ZHANG
《农业科学与工程前沿(英文)》 2016年 第3卷 第1期 页码 65-71 doi: 10.15302/J-FASE-2016086
关键词: PRRSV porcine sialoadhesin V-set Ig-like domain Drosophila S2 cell crystallization
From SARS to MERS: evidence and speculation
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《医学前沿(英文)》 2016年 第10卷 第4期 页码 377-382 doi: 10.1007/s11684-016-0466-7
The Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel zoonotic pathogen. In 2012, the infectious outbreak caused by MERS-CoV in Saudi Arabia has spread to more than 1600 patients in 26 countries, resulting in over 600 deaths. Without a travel history, few clinical and radiological features can reliably differentiate MERS from SARS. But in real world, comparing with SARS, MERS presents more vaguely defined epidemiology, more severe symptoms, and higher case fatality rate. In this review, we summarize the recent findings in the field of MERS-CoV, especially its molecular virology, interspecies mechanisms, clinical features, antiviral therapies, and the further investigation into this disease. As a newly emerging virus, many questions are not fully answered, including the exact mode of transmission chain, geographical distribution, and animal origins. Furthermore, a new protocol needs to be launched to rapidly evaluate the effects of unproven antiviral drugs and vaccine to fasten the clinical application of new drugs.
关键词: middle east respiratory syndrome animal origin cross-species transmission monoclonal antibody
A brief review of microRNA and its role in PRRSV infection and replication
Xuekun GUO,Wenhai FENG
《农业科学与工程前沿(英文)》 2014年 第1卷 第2期 页码 114-120 doi: 10.15302/J-FASE-2014022
关键词: porcine reproductive and respiratory syndrome virus (PRRSV) microRNA antiviral viral tropism
临床诊断标准实施和全城症状排查对武汉新冠病毒肺炎疫情防控的效果评价 Article
魏永越, 魏良敏, 姜玥, 沈思鹏, 赵杨, 郝元涛, 杜志成, 唐金陵, 张志杰, 姜庆五, 李立明, 陈峰, 沈洪兵
《工程(英文)》 2020年 第6卷 第10期 页码 1141-1146 doi: 10.1016/j.eng.2020.04.008
自新型冠状病毒肺炎(coronavirus disease 2019, COVID-19)疫情发生以来,中国大多数的病例集中在武汉市。虽然早期病例数和死亡人数迅速增加,但通过采取多种防控措施,疫情得以快速遏制。纵观全球,疫情已蔓延至全球六大洲的187个国家,确诊病例数已超过300万,这一数字仍在快速增长。在此特殊背景下,有必要对我国疫情防控措施开展科学的、定量的评估,为全球疫情防控提供决策依据。为此,本研究评估了临床诊断标准实施和全城症状排查对武汉市疫情控制的贡献。考虑COVID-19的传播机理、隔离措施等,建立SEIR+Q传播动力学模型。基于武汉市截至2020年2月14日官方公布的每日确诊病例数和未确诊的临床诊断病例数进行建模,并预测2月14日以后的疫情态势。基于实际疫情数据,与模型预测趋势相比较,评价防控措施效果。结果显示,若维持2月14日以前防控措施不变,那么预测将于3月25日和4月29日,每日新增病例数分别降至100例和10例以下,将于5月31日首次现零。而事实上,截至3月6日,武汉市每日新增病例数降至100例以下,截至3月11日降至10例以下,3月18日首次实现零增长,较之模型预测结果分别提前了19 d、49 d和74 d。截至3月30日,实际累计病例数为50 006例,比模型预测值减少19 951例。有效再生数[effective reproductive number, R(t)]分析显示,2月6−10日的第一次全城症状排查后,R(t)显现出下降趋势,2月12−14日的临床诊断标准实施和2月17−19日的第二次全城症状排查后,R(t)显现出较大的降幅,与实际情况较为一致。综上所述,武汉市临床诊断标准的实施和全城症状排查等综合防控措施成效显著,可为世界各国的疫情防控决策提供科学依据。
何平
《中国工程科学》 2003年 第5卷 第7期 页码 40-46
对系统非优分析理论做了较为详细的论述。指出寻求不确定系统优化的主要问题,关键是缺少对系统的非优分析。在系统非优范畴的基础上建立了征兆群与经验分析,提出了系统非优度量以及从非优追踪到系统自组织等问题。
标题 作者 时间 类型 操作
Effect of laparoscopic fundoplication treatment on gastroesophageal reflux disease-related respiratory
Zhong-Gao WANG MD, FACS, Feng JI MD, PhD, Yun-Gang LAI MD, PhD, Xiang GAO MD, PhD, Cheng-Chao ZHANG MD, PhD, Ji-Min WU MD, PhD, Xiu CHEN MD, PhD, Ibrahim M. IBRAHIM MD, FACS,
期刊论文
patients at high risk of OSAS using the Berlin Questionnaire to detect potential high risk of adverse respiratory
null
期刊论文
A pilot study on Paxlovid therapy for hemodialysis patients with severe acute respiratory syndrome coronavirus
期刊论文
Middle East respiratory syndrome coronavirus: current situation and travel-associated concerns
null
期刊论文
Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia
Sarah H. Alfaraj, Jaffar A. Al-Tawfiq, Talal A. Altuwaijri, Ziad A. Memish
期刊论文
Early and marked up-regulation of TNF-α in acute respiratory distress syndrome after cardiopulmonary
null
期刊论文
Characterization of polyclonal antibodies against nonstructural protein 9 from the porcine reproductive and respiratory
Mengmeng ZHAO,Juanjuan QIAN,Jiexiong XIE,Tiantian CUI,Songling FENG,Guoqiang WANG,Ruining WANG,Guihong ZHANG
期刊论文
Serologic study on the outbreak of acute upper respiratory tract infections caused by adenovirus 3
JIANG Lufang, JU Liwen, LIN Yuzun, ZHOU Liandi, YU Shunzhang, JIANG Qingwu, JIANG Renjie
期刊论文
porcine sialoadhesin V-set Ig-like domain sheds some light on its role in porcine reproductive and respiratory
Jie HOU,Rui LI,Hongfang MA,Songlin QIAO,Gaiping ZHANG
期刊论文
A brief review of microRNA and its role in PRRSV infection and replication
Xuekun GUO,Wenhai FENG
期刊论文